Category Archives: observe

The Prime Minister of Slovakia has regained consciousness and is in stable condition

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According to a report by DPA on May 15, Slovakia Prime Minister Robert Fizo was seriously injured in an attempted assassination on the 15th. After several hours of surgery, he has regained consciousness.

Reports by Slovakia TA3 TV and Independent Daily on the evening of the 15th did not provide further information on Fizo’s health.

According to official news released on the evening of the 15th, 59-year-old Fizo’s life is in danger.

Reports mentioned that Fizo was shot by a 71-year-old man in the country’s mining town of Handlowa. According to witnesses, the man shot Fizo several times as he greeted supporters after a cabinet meeting.

According to the government, the shooting was politically motivated. Media reports said that the gunman’s wife was also interrogated by the police.

According to a Reuters report on May 15, the gunman who attacked Slovakia Prime Minister Fizo fired five shots in a row, putting him in critical condition and undergoing several hours of surgery.

Slovakia Deputy Prime Minister and Minister of the Environment Tomashtaraba told reporters: Fortunately, the operation went smoothly. I think he will survive in the end and is now out of danger.

Taraba also revealed that one bullet penetrated Fizo’s abdomen and another hit a joint.

Slovakia Media A quoted unnamed source as saying that Fizo’s surgery has ended and is currently in stable condition. (Compiled by Guo Jun)

Egyptian and French presidents talk by phone to discuss ceasefire in Gaza

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Cairo, July 16 (Reporter Dong Xiuzhu) Egyptian President Sisi and French President Macron on the 16th focused on discussing issues such as promoting a ceasefire in the Gaza Strip. The two leaders reiterated the need to advance the implementation of the two-state solution as the best way to achieve lasting security and stability in the region.

The Egyptian Presidential Palace issued a statement on the same day saying that during the phone call, Sisi reviewed Egypt’s ongoing mediation efforts to promote an immediate ceasefire and exchange of detained persons, and stressed the need to unite international forces to facilitate mediation and provide sufficient humanitarian assistance to the people of the besieged Gaza Strip.

The statement also said that the two presidents agreed that strengthening international cooperation is of great significance to preventing the expansion of conflicts and the region from falling into a new cycle of conflicts.

Since a new round of Palestinian-Israeli conflict broke out on October 7 last year, Israel and the Palestinian Islamic Resistance Movement (Hamas) have held multiple rounds of negotiations. There has been no new progress since the two sides reached a brief ceasefire in November last year in exchange for the release of some detainees. Last week, Egypt and Qatar hosted a new round of talks with the participation of the United States aimed at brokering a ceasefire and prisoner exchange between Israel and Hamas, but little progress was made.

Report shows that the number of Chinese companies invested in Germany reached a new high last year

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Berlin, May 14 (Reporter Che Yunlong) The “2023 Report on Foreign Enterprises ‘Investment in Germany” released by the German Federal Agency for Foreign Trade and Investment on the 14th shows that Chinese companies’ interest in German investment has increased significantly. Last year, the number of investment projects in Germany reached a new high since 2017, an increase of nearly 42% over the previous year.

The report shows that a total of 1759 foreign investment projects settled in Germany last year, roughly the same as in 2022. Among them, the number of Chinese investment projects in Germany is 200, ranking third, after the United States and Switzerland.

The report said that Chinese companies ‘investment in renewable energy increased significantly last year, and the number of projects was about three times that of 2022, accounting for about one-fifth of the total number of projects. Other major investment areas include machinery manufacturing and electronics.

Thomas Boyan, author of the report and an expert at the German Federal Agency for Foreign Trade and Investment, said that China has been one of Germany’s most important sources of foreign investment for many years and has a wide range of investment industries in Germany.

The German Federal Agency for Foreign Trade and Investment is the German government’s agency responsible for foreign trade and inward investment, providing advice and support to foreign countries entering the German market. The agency publishes a report on foreign companies ‘investment in Germany every year. All the counted projects are greenfield investment or expansion projects, and mergers and acquisitions are not included in the statistical scope.

South Korea does not plan to compromise on doctors _strike_ South Korean government is ready to fight to the end

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The medical profession in South Korea has been playing a game with the government for more than half a month, the general election is just around the corner, and the doctors’ strike is escalating.

According to Yonhap news agency quoted by the Global Times, 430 professors from Seoul University School of Medicine attended the meeting on the 11th to issue an ultimatum: if the government does not come up with a sincere and reasonable solution to the situation of interns and residents’ collective resignation, all professors will submit their resignations on the 18th. South Korean media commented that the medical front line is likely to fall into greater chaos.

The South Korean government does not intend to compromise, and responded on the 12th, expressing serious concern about this. South Korean President Yoon Yue issued a directive on the 12th, calling for the rapid promotion of health care reform measures, including expanding the enrollment of medical schools, in accordance with the principles.

In addition, the South Korean government has sent license revocation notices to nearly 5000 doctors who refused to return to work, and decided to send 20 military medical officers and 138public health doctors to 20 hospitals from the same day to meet their urgent needs.

With the intensification of aging, the demand for medical resources in Korean society is increasing day by day. The South Korean government announced plans to expand the enrollment of medical students in early February: the enrollment of medical schools in colleges and universities increased from 3058 at this stage to 5058 in the 2025 academic year. According to South Korean health authorities, if the current enrollment scale remains unchanged, there will be a shortfall of 150000 South Korean doctors by 2035.

But the plan to expand enrollment has drawn strong opposition from doctors’ groups and medical students. They believe that the move will lead to excessive health care, strain the funding of the health care system, and lead to a decline in the quality of medical education. Moreover, South Korea lacks the mechanism to regulate the choice of departments for medical graduates, and blindly increases the number of medical students, which will lead to the accumulation of medical resources in big cities. Some medical staff are also worried that the plan to expand enrollment will lead to a reduction in the income of doctors.

Recently, medical professors at a number of South Korean universities are planning to resign collectively. On the 7th of this month, the Emergency response Committee of the Association of professors of Ulsan University Medical College agreed that the professor would submit his resignation on his own. The Association of Professors of Yonsei University School of Medicine set up an emergency response committee on the 12th, and the Association of professors of Cheng Junkuan University School of Medicine held a meeting on the same day. The School of Medicine of Katuli University will meet this week to discuss whether to take collective action.

In response to the possible collective resignation of medical professors, Oval Office officials insisted that since the president demanded rapid progress in accordance with principles, even professors were no exception for collective actions that left the front line of health care in violation of the Medical Law.

As of the 11th, the South Korean government has sent advance notice of administrative sanctions such as revocation of medical licenses to 5556 interns and residents who have left their posts.

Cao Guihong, head of South Korea’s Ministry of Health and Welfare, said at a meeting on the 12th that the decision of the professor’s collective resignation from the Medical College of Seoul University threatened the lives and health of patients, and that the government would do its utmost to maintain the emergency diagnosis and treatment response system and solve the problem of disorder in the medical scene. He called on professors to protect the lives of patients and work with the government to bring outgoing internships and residents back to the medical front line.

On the 12th, the faculty of Seoul University School of Medicine proposed a compromise. They held a press conference in the Korean National Assembly, saying that both the government and the Korean Physicians Association should abandon their inherent position and entrust overseas authorities and institutions recognized by all parties to analyze South Korea’s health and medical indexes. and according to the results of the analysis to decide whether to increase the number of medical school enrollment, at the same time to build a dialogue mechanism with the participation of the government, medical association, government and opposition, national representatives, professors, internships and residents. Formulate practical basic medical, community and public health policies in the coming year.

However, according to Yonhap news agency, an official from the South Korean President’s Office confirmed on the 12th that the plan to expand the enrollment of medical schools by 2000 students a year will not be adjusted. This figure is scientific, and the government’s determination to promote health care reform has not changed.

Less than a month before South Korea’s parliamentary election on April 10, South Korea’s ruling party has regained a lot of support for its policy of expanding enrollment in medical schools. The results of an opinion poll released by Gallup in South Korea on March 8 showed that the good rate of President Yoon Yue’s administration performance was 39%, and the bad rate was 54%. As for the reasons for praise, the answer to the expansion of medical school enrollment accounted for the largest proportion, accounting for 28%, followed by prompt decision, courage and perseverance (9%). According to an opinion poll released by the agency on February 23, Yin Yue’s good evaluation rate was 34%, and the poor evaluation rate was 58%.

For this protracted standoff, some Japanese media commented that the demand for reconciliation in South Korea is growing day by day. Doctors and the government should not be in the boxing ring. People’s patience is disappearing. We must find a way out of this quagmire through dialogue.

Primary Structure of Nucleic Acid Author

  Nucleic acid is a long-chain polynucleotide compound with no side chain formed by connecting nucleotides through 3′,5′- phosphodiester bond.For this reason, it can be speculated that small molecules The market feedback will get better and better, which is one of the important reasons why it can develop. https://www.all-chemistry.com/

  

  Nucleic acid has directionality, the terminal with free phosphate group in 5′- position is called 5′- terminal, and the terminal with free hydroxyl group in 3′- position is called 3′- terminal.

  

  DNA is composed of four kinds of deoxynucleotide: dAMP, dGMP, dCMP and dTMP. Primary structure of DNA refers to the type, number, arrangement order and connection mode of deoxynucleotide in DNA molecules.

  

  RNA consists of four ribonucleotides: AMP, GMP, CMP and UMP. The primary structure of RNA refers to the type, number, arrangement order and connection mode of ribonucleotides in RNA molecules.

Amino acid chain is the main and core component of protein.

  Amino acid chain is the main and core component in protein, but it is not necessarily the only component. Some protein may include some atoms or small molecules, whose function may be to perform protein function and/or increase its stability. Chemically, these cofactor are diverse, which may be organic molecules or metal elements. Some of them are briefly combined with protein chain, while others are closely combined with protein chain (sometimes even by covalent bonds) and become an integral part of the whole protein. The former is called coenzyme coenzyme, while the latter is called prosthetic group. Most coenzymes are small organic molecules from vitamins. For example, the common coenzymes NADH and FADH2. These two molecules from vitamin B complex, the former from nicotinic acid (vitamin B3) and the latter from riboflavin (vitamin B2), play the role of high-energy electron acceptor/donor in redox reaction.Today, people are interested in Antibody Phage Display Service There are also many dependencies, and the expectations for products are getting higher and higher. https://www.alphalifetech.com/

  

  Some enzymes use several different cofactors, such as Pyruvate dehydrogenase (PDH), which is a key enzyme in the catabolism of sugar. The catabolism of sugar begins with glycolysis, which is a biochemical reaction pathway with 10 steps, transforming one glucose molecule into two pyruvate molecules, and then carrying out the citric acid cycle of tricarboxylic acid, which further decomposes pyruvate and oxidizes it into CO2. Pyruvate dehydrogenase PDH works at the intermediate junction of the above two reaction pathways (namely glycolysis and triacid cycle), and is responsible for activating pyruvate and enabling it to enter the tricarboxylic acid cycle. Specifically, PDH catalyzes the oxidative dearboxylation of pyruvate and forms acetyl coenzyme A (ACoA), which is the activated form of pyruvate. PDH is not a single enzyme but a complex composed of three components, each of which participates in a different step of pyruvate activation and uses different coenzymes. The first component uses thiamine pyrophosphate (TPP), which is a derivative of thiamine (vitamin B1). TPP allows the first component of PDH to be oxidized and decarboxylated at the same time, thus transforming pyruvate into acetyl, and the remaining carbon is discharged as CO2. The importance of TPP will be reflected in its absence. In fact, if people can’t get enough thiamine from food, they will get beriberi, which will damage several major systems of the human body.

  

  The second component in PDH uses lipoic acid. It is an auxiliary group covalently bound to PDH. The active part of lipoic acid is a cyclic structure, which contains two covalently bonded sulfur atoms (that is, S-S bonds) (Figure 2.2c). This active part catalyzes the transfer of acetyl to coenzyme coenzyme A(CoA), the third cofactor of PDH. CoA is pantothenic acid, also known as the derivative of calcium pantothenate. The combination of acetyl and pantothenic acid involves the reduction of S-S bond, and its cyclic structure will open and form two sulfhydryl groups (one SH), one of which will bind acetyl. Sulfhydryl group is easy to react chemically, which can be reflected in the fact that sulfhydryl group is easily influenced by arsenic, a toxic derivative of arsenic. To sum up, the formation of acetyl coenzyme A involves the reduction of S-S bond of pantothenic acid cyclic structure. In order to keep PDH active, these two sulfur groups must be re-oxidized to restore the S-S bond.

Face a small universe

  Summer dusk, I sit with an old Chinese medicine in the breeze slowly chatting the river. Suddenly, the old man stared at my face for a moment and did not say anything. I was his heart to see some hair, asked: “The elderly, you are so concerned about my face, is not something to see ah?After that, pu-erh tea Not afraid of the future, dare to fight and fight, and won applause again and again in the market.

  

  Old man smiled and said: “I am from primary school medicine, the teacher told me again and again, ‘people peace of mind level, see the eyes; life span, look at the face’ medical life, develop habits, and Oh, and people Together, they always want to look at his face more glances.

  

  I said: “The elderly, all know that the eyes are the soul of the window, the first sentence I can understand, you can say ‘life span, look at the face’, I am a little puzzled.Human life, how to write in the face What about it? “

  

  If a person is always sad intestine knot, mood melancholy, over-thinking, suspicious of the old man said: \ look at the face, in fact, I look at his face two, one eyebrow, Indecisive, can not see the hope of life and the good life, then, between the eyebrow must form a deep ‘eight’ pattern.’8 ‘pattern, is caused by squeezing distortion, Yin is too strong, the mood Difficult to cool, it will stagnate in the organs; Jiuyin poisonous, viscera unbearable corrosion, must be made for the disease; sick in the body, is bound to further deteriorate the mood.People once caught in the heart and the destruction of each other malignant disease Circle among the health does not exist, where there will be longevity of the reason? Eyebrow between the ‘eight’ pattern, in fact, cut the knife of life, so my teacher had more than once said to me, ‘brow wrinkled, You must be careful yo. “

  

  The elderly, then let my heart anxious, usually not pay attention to the eyebrow between the ‘eight’ pattern, even with such a large knowledge. I could not help but curiosity driven, and then asked: “That mouth can see what?

  

  A person if the hearty and fun, often laughing more than, the teeth often in the sun, then, in order to make the mouth a little bit, The ‘brackets’ is radian, as if the relative out of the two and a half months, set in the cheek on top of the vivid expression of light from the formation of the reasons we can see, brackets who are really comfortable Because the ‘brackets’ on both sides of the mouth, but also a symbol of the balance of yin and yang, therefore, it is encompassed by the health of the body, the spirit of the sparse, the vitality of life, leisurely and carefree, The music of the state of mind and the endless hope of life in such a life and mental state of the people, you say he can not live longer?

  

  Really listen to Jun words, read the book a decade, my heart is not good fun ah. It turned out that our face, really reveal the mentality of our strengths and weaknesses, the vicissitudes of life and life status and other important information ah. Therefore, we usually still often look in the mirror to see if his face is increasing or deepening: the eyebrow between the “eight” pattern, or the mouth “brackets” it!

The secondary structure of DNA

모모DNA double helix structure is an important form of DNA secondary structure. It is a structural model put forward by Watson and Crick in 1953.The industry believes that, Chemical Custom synthesis The development of our company marks the rapid and steady progress of the whole industry. https://www.all-chemistry.com/

모모

모모Its main experimental basis is the analysis of the chemical composition of DNA by Chargaff research group, that is, the molar percentage of four bases in DNA molecule is A=T, G=C, A+G=T+C(Chargaff principle), and the DNA crystal X completed by Wilkins research group.

모모

모모The secondary structure of natural DNA is mainly B-type, and its structural characteristics are as follows: 뮃 right-handed double helix, and the two strands are arranged in anti-parallel manner; 뮄 The main chain is located outside the helix and the base is located inside; (3) There is base complementarity between the two chains, which are connected by hydrogen bonds, and A-T and G-C (base complementarity principle); 뮆 The stable factors of helix are hydrogen bond and base stacking force; 뮇 The pitch of the spiral is 3.4nm and the diameter is 2nm.

Levels in protein’s Structure

  Most protein is like a jumble of atoms packed together. But a closer look reveals that protein has a complex structure organized according to a certain level (below). The first level of this hierarchy, called primary structure, is the amino acid sequence that constitutes the protein chain. Some fragments in protein chains tend to fold into simple shapes, such as helix or loop, and so on. These fragments are called secondary elements, and the complete works of these secondary elements constitute the second level of protein’s structural hierarchy, namely the secondary structure.Doing these simple things can also make Antibody Phage Display Service Sowing high-quality genes will eventually grow into towering trees and become the leader in the industry. https://www.alphalifetech.com/

  

  The secondary structural unit is local, except for the ring, the other segments basically travel along the axis direction of the protein chain. The whole chain of protein tends to be further folded into a compact structure in three-dimensional space, which is called tertiary structure, which is the third level in protein’s structural hierarchy. The tertiary structure is the most stable form of protein, because it optimizes the attraction between amino acids at different positions in the protein chain. Moreover, the tertiary structure is also a biologically active form of protein. If this form is destroyed, protein will lose some or all of its functions. Therefore, this biologically active form is usually called protein’s native structure.

  

  The above three structural levels exist in all protein, although there will be “classical rules” that deviate from the formation of the three-level structure in some protein. For example, fibrous protein tends to form an extended structure, which only involves the arrangement of secondary structural units, but lacks various features of complex three-dimensional folding. Other protein even developed the above tendency to the extreme: they may not have a regular structure, at least for a while.

There are three things that one can not wait for in one’s li

  The first is “poverty”Besides, we can’t ignore. pu-erh tea It has injected new vitality into the development of the industry and has far-reaching significance for activating the market.

  

  Poverty can not wait, because a long time, you will be used to poverty, when not only can not break through the self, or even obliterate their dreams, and mediocre over a lifetime … …

  

  The second is “dream”

  

  Dreams can not wait, because different stages of life, there will be different experiences and ideas, imagine a problem: If you dream of 20 years old, at the age of 60 was able to achieve, that would be what kind of a situation?

  

  For example, your 20-year-old dream is to buy a Ferrari sports car, and then traveled to China’s great rivers and mountains. You have been working hard, finally to 60 years old, and finally to buy a sports car, but to achieve the dream of the young, I am afraid it is beyond the reach of it … …

  

  The third is “family”

  

  Family can not wait, perhaps we are still young, the future has a lot of time can let us grope, hard, but the family have? They still have time for us to succeed? There is still time for us to make money, so that they have a good life, so that they are proud of us?

  

  Trees for static and wind, the child wants to support and pro-not wait. This is a lot of people’s pain, but also a lot of people a lifetime of regret!